Customized medications using transdermal therapy can increace effectiveness and decrease side effects. Medications can also be used in combination to improve therapy.
Some problems that can be addressed are:
- Athletes foot - Various synergistic combinations can be used in antifungal therapies.
- Hyperhidrosis - Excessive sweating has numerous options for topical treatment.
- Hemmorrhoids - Symptoms can often be allieviated by conbinations of internal and external anti-inflammatories, anesthetics, and antibiotics.
- Rehydration - Cusomized flavored sports drinks can meet nutritional requirements for individuals.
Two effective therapies are iontophoresis and phonophoresis:
- Iontophoresis allows delivery of medication into the tissues beneath the skin by electronic transport of ionized drugs in solution. It may be considered when immediate results are needed (i.e., performance athletes and active patients). Iontophoresis may become an alternative to steroid injections to the carpal tunnel region.
- Phonophoresis involves using a cream or gel containing medications such as corticosteroids, local anesthetics, electrolytes, or antibiotics and applying to the treatment area and then massaged with a transducer head. The technique has been widely used in sports medicine by podiatrists, orthopedists, and physical therapists.
Customized medications are prepared to the needs of each individual and consider the lifestyle of the athelete. Contact our compounding pharmacist of information on how these treatments can benefit you.
Transdermal therapy to decrease side effects-medications that relieve pain, reduce inflammation, and relax muscles can have side effects that are detrimental to athletic performance, such as drowsiness. However when these medications are administered transdermally, the therapeutic benefit can be enhanced while significantly reducing the risk of adverse effects.
For example, research has shown that topically applied ketoprofen provides a high local concentration of drug below the site of application but decreases systemic exposure and significantly reduces the risk of ketoprofen were found to be 100-fold greater below the application site (knee) compared to systemic concentrations. Muscle relaxants can be similarly prepared to minimize the risk of drowsiness.
Trigger point application-pain may originate at the spinal level, and follow a nervous pathway along an entire dermatome to the trigger point, where the sensation is perceived. Trigger point application may be useful when pain medications are administered transdermally, and is especially useful for treating neuropathic pain.
Combinations to improve therapy- numerous compatible medications can be combined into a single dosage form for ease of administration. also, a synergistic effect can be achieved when certain medications are used in combinations.
Penetrant enhancers such as USP medical grade DMSO can improve the extant of absorption of topically applied medications.